OTF may refer to:
Science and technology OTF knife, or sliding knife, a type of pocketknife OpenType, a standard for digital typography (file extension .otf) Optical transfer function, a metric for evaluating optical systems Triflate, in organic chemistry, a functional group represented by the symbol -OTf Off-the-film metering, in camera metering systems, a type of through-the-lens metering
Other uses Order of the Falcon, order of chivalry in Iceland Obstructing the field, an infringement in cricket Only the Family, an American hip-hop collective and the associated record label, OTF Ontario Teachers' Federation, Canada Open Technology Fund, an American nonprofit corporation