Constance of Castile may refer to:

Constance of Castile, Queen of France (died 1160), daughter of Alfonso VII of Castiel and wife of Louis VII of France , daughter of Alfonso VIII of Castile , daughter of Alfonso X of Castile Constanza Manuel (died 1345), daughter of Juan Manuel and wife of Alfonso XI of Castile and Peter I of Portugal Constance of Castile, Duchess of Lancaster (1354–1394), daughter of Peter of Castile and wife of John of Gaunt, claimant to the throne of Castile Constance of Castile (died 1478), granddaughter of Peter of Castile and abbess of Santo Domingo el Real en Madrid