Bottlebrush may refer to:
A type of brush intended for cleaning bottles Any of several plants commonly known as bottlebrush Callistemon, a genus of shrubs and trees from Australia Beaufortia, a genus of shrubs from Australia Elymus hystrix, a species of grass from eastern North America Elymus californicus, a species of grass from California Bottlebrush (cave formation)
See also Bottlebrush buckeye, a species of shrub from the southeastern United States