William Griffith may refer to:
Politicians William Griffith the Hael (c. 1445–c. 1540), Welsh politician William Griffith (born 1480) (1480–1545), his son, Welsh politician William Griffith (MP fl.1586), member of parliament (MP) for Caernarvon Boroughs William Griffith (MP fl.1597), MP for Caernarvonshire William Griffith (1620–1688), Welsh MP for Caernarvon William Griffith (1686–1715), Welsh MP for Caernarvon and Caernarvonshire William Griffith (US politician), see United States House of Representatives elections, 2006 William B. Griffith (1795–1827), American attorney and orator William Downes Griffith (1829–1908), Irish politician and attorney general of the Cape Colony
Sports Billy Griffith (footballer) (William Charles Griffith, 1880–1949), Australian rules footballer William Griffith (canoeist) (born 1947), Canadian canoeist William Griffith (cricketer) (1871-1948), South African cricketer
Others William Griffith (New Jersey attorney) (1766–1826), briefly served as a United States federal judge William Griffith (astronomer) (born 1956), Californian amateur astronomer William Griffith (botanist) (1810–1845) Bill Griffith (William Henry Jackson Griffith, born 1944), American cartoonist William Griffith (murderer) (died 1863), participant in the Marais des Cygnes massacre, for which he was later executed William Alexander Griffith (1866–1940), American painter and educator William Pettit Griffith (1815–1884), English architect and antiquarian
See also William Griffiths (disambiguation) Billy Griffith (Stewart Cathie Griffith, 1914–1993), English cricketer Bill J. Griffith (1905–1994), Australian rules footballer