Safed massacre relates to several violent events, happening throughout different time periods in the town of Safed (Tzfat), Galilee in Israel.

Safed massacre may refer to: 1517 Safed attacks 1660 destruction of Safed, part of the Druze power struggle (1658–67) 1834 looting of Safed, part of the Syrian Peasant Revolt (1834–35) 1838 Druze attack on Safed, part of the 1838 Druze revolt 1929 Safed massacre, part of the 1929 Palestine riots

See also History of the Jews and Judaism in the Land of Israel List of massacres in Ottoman Syria List of killings and massacres in Mandatory Palestine