GOF may refer to:
Arts and entertainment Galaxy on Fire, a video game series Harry Potter and the Goblet of Fire, a 2000 novel by J. K. Rowling
Organisations Gamers Outreach Foundation, an American philanthropic organization General Operations Force, of the Malaysian police Grand Orient de France, a Masonic organization in France An Gof, a Cornish militant organization
Places Gulf of Finland Golf Street railway station, in Angus, Scotland
Other uses Gain-of-function, a property of a genetic mutation Gamo-Gofa-Dawro language, spoken in Ethiopia Gang of Four (disambiguation) Goodness of fit