Audrain may refer to:
Ashley Audrain (born 1982), Canadian author François Audrain, French singer and songwriter James Hunter Audrain (1781–1831), colonel of militia in War of 1812 and member of Missouri state legislature Audrain County, Missouri, county in Missouri, United States USS Audrain (APA-59), United States Navy Gilliam class attack transport that served during World War II
See also Adrain Adrian (disambiguation)