Kilkenny is a surname. Notable persons with that surname include:
Allison Kilkenny (born 1983), American journalist and podcaster Jimmy Kilkenny (1934–2003), footballer John C. Kilkenny, film executive John Kilkenny (1901–1995), U.S. federal judge Mike Kilkenny (1945–2018), Canadian baseball player Neil Kilkenny (born 1985), English-born Australian footballer Niamh Kilkenny (born 1989), camogie player Ollie Kilkenny (born 1962), hurler Tony Kilkenny (born 1959), hurler