Guana may refer to:
Places Guana Island, an island in the British Virgin Islands Guiana Island (Antigua and Barbuda), also called Guana Island, off Antigua Guana River, in Guana Tolomato Matanzas National Estuarine Research Reserve, in Florida, U.S.
Languages Guana language (Brazil), a language of the Brazilian Terêna Guana language (Paraguay), a language of the Paraguayan Chaco
Other uses Guana people, or Chané, an ethnic group in Paraguay, Bolivia, Argentina, and Brazil Roberto Guana (born 1981), footballer
See also Guyana (disambiguation) Iguana (disambiguation)