Francis Loomis may refer to:
Francis Loomis (Connecticut politician) (1812–1892), 58th Lieutenant Governor of Connecticut Francis Butler Loomis (1861–1948), 25th United States Assistant Secretary of State Francis Wheeler Loomis (1889–1976), American scientist Francis B. Loomis Jr. (1903–1989), United States Marine Corps general
See also Frank Loomis (1896–1971), American athlete Loomis (surname)