HRG may refer to:

Science Hemispherical resonator gyroscope Histidine-rich glycoprotein, a plasma protein Horizontal ribbon growth, a method of crystal growth HRG, a Rockwell scale of materials' hardness Human reference genome

Organizations HRG Engineering Company, a British car manufacturer HRG Group, an American holding company Healthcare Resource Group, within the English healthcare system Henley Residents Group, an English political party Hogg Robinson Group, a defunct corporate travel management company Home Retail Group, an English company Hostage Response Group of New South Wales, Australia

People Branko Hrg (born 1961), Croatian politician Noah Bennet ( Horn Rimmed Glasses), a character in the TV series Heroes

Other Hurghada International Airport, in Egypt