Pernet is a French surname. Notable people with the surname include:
André Pernet (1894–1966), French opera singer Diane Pernet, French fashion designer Étienne Pernet (1824–1899), founder of the Little Sisters of the Assumption Order Heinz Pernet, German-born Nazi Party leader Jean Pernet, père (1832–1896), French rosarian Johannes Pernet (1845-1902), Swiss physicist Joseph Pernet-Ducher (1859–1928), French rosarian