Poughkeepsie is a city in Dutchess County, New York, United States.

Poughkeepsie can also refer to: Relating to Poughkeepsie, New York: Poughkeepsie (Metro-North station), a railroad station in the city Poughkeepsie (town), New York, a town surrounding the city The Poughkeepsie Tapes, a 2007 film based in and named after the aforementioned city. Poughkeepsie, Arkansas, an unincorporated area in Sharp County, Arkansas