UCSC is the University of California, Santa Cruz, a public research university in Santa Cruz, California, United States.
UCSC may also refer to:
Università Cattolica del Sacro Cuore, a private Catholic university based in Milan, Italy University of Colombo School of Computing, a college affiliated with the University of Colombo in Sri Lanka University City Science Center, an urban research park in Philadelphia, Pennsylvania, United States Universidad Católica de la Santísima Concepción, a private catholic university in Chile