George Spencer-Churchill may refer to:
George Spencer-Churchill, 5th Duke of Marlborough (1766–1840) George Spencer-Churchill, 6th Duke of Marlborough (1793–1857) George Spencer-Churchill, 8th Duke of Marlborough (1844–1892) George Spencer-Churchill, Marquess of Blandford (born 1992), elder son of Charles, 12th Duke of Marlborough, oldest surviving son of John, 11th Duke of Marlborough
See also George Spencer (disambiguation) George Churchill (disambiguation)