Quarles is a surname, and may refer to:
Benjamin Arthur Quarles (1904–1996), historian, administrator, scholar, educator Christina Quarles (born 1985), artist Donald A. Quarles (1894–1959), communications engineer, executive Francis Quarles (1592–1644), poet Greenfield Quarles (1847–1921), soldier, judge James Minor Quarles (1823–1901), American politician John Quarles (1624–1665), poet Joseph V. Quarles (1843–1911), American politician Julian Minor Quarles (1848–1929), American politician Nancy L. Quarles (born 1951), American politician Randal Quarles (born 1957), managing director Ryan Quarles (born 1983), American politician Shelton Quarles (born 1971), sportsman Tunstal Quarles (1781–1856) William Andrew Quarles (1825–1893), American lawyer, politician, railroad executive from Tennessee William D. Quarles Jr. (born 1948), American jurist William Quarles (cricketer) (1800–1879), English cricketer Quarles, Quarles de Quarles or Quarles van Ufford, a Dutch noble family of English descent. Quarles was a pseudonym used by Edgar Allan Poe for 'The Raven'.
Quarles is a place, and may refer to: Quarles, Norfolk, England Quarles, Missouri, United States Quarles Range, a mountain range in Antarctica
See also Quarles & Brady LLP, U.S. law firm New York v. Quarles, a 1984 U.S. Supreme Court case