Matthew or Matt Thompson may refer to:

Entertainment Matthew Thompson (actor), American actor Matthew Thompson (writer), American-born Australian writer Matt Thompson (animator), American producer, writer, and voice actor in animation Matt Thompson (film director) (born 1984), American film director, producer, screenwriter and actor

Sports Matthew Thompson (cricketer) (born 1974), English cricketer Matt Thompson (soccer) (born 1982), Australian footballer Matt Thompson (rugby union) (born 1982), English rugby union player

Other Matthew William Thompson (1820–1891), British MP for Bradford, West Yorkshire, 1867–1868 Matt Thompson (priest) (born 1968), British Anglican priest Matt Thompson (journalist) (born 1980), American journalist and member of the Center for Investigative Reporting

See also Mat Roy Thompson (1874–1962), civil engineer and builder of Scotty's Castle Matthew Thomson (disambiguation)