NPL may refer to:

Sport National Pickleball League of Champions Pros, an American professional pickleball league for senior players National Pickleball League Australia, an Australian professional pickleball league National Pool League, a defunct American pool league Nepal Premier League, a professional cricket league

Football Namibia Premier League, the defunct top tier of football in Namibia National Premier League, the top tier of football in Jamaica National Premier Leagues, the second tier of men's football in Australia National Premier Leagues Women's, the second tier of women's football in Australia Nigerian Premier League, the top tier of football in Nigeria Northern Premier League, at the seventh and eighth tier of football in England Northern Premier League (Tasmania), a third-tier football league in Australia covering northern Tasmania Norwegian Premier League, the top tier of football in Norway

Computing Netscape Public License, a free software license New programming language, the original name of PL/I by IBM in 1964 Nonprocedural language, by T.D. Truitt et al. in 1980 NPL programming language, a functional programming language by Rod Burstall and John Darlington in 1977 NORD Programming Language, an internal systems language used at Norsk Data NPL network, a computer network from 1967 until 1986, a precursor to the internet

Organizations National Party of Liberia National Puzzlers' League, the oldest puzzlers' organization in the world Nonpartisan League, an American socialist political organization National Physical Laboratory (United Kingdom) National Physical Laboratory of India New Paradise Laboratories, an experimental theater ensemble in Pennsylvania, USA

Places Nepal (ISO 3166-1 alpha-3 code) New Plymouth Airport (IATA code), New Zealand

Other uses National Priorities List, an EPA list of hazardous waste sites in the United States Nauru Pacific Line, the national shipping line of the Republic of Nauru Non-Patent Literature, used before the United States Patent and Trademark Office Non-performing loan, a loan close to, or in default Novgorod First Chronicle (Novgorodskaia pervaia letopis’), the oldest extant Rus' chronicle of the Novgorod Republic Nuclear pumped laser, a laser pumped with the energy of fission fragments

See also NPL SA, the National Premier Leagues South Australia