Antigonus or Antigonos (), a Greek name meaning "comparable to his father" or "worthy of his father", may refer to:

Rulers Three Macedonian kings of the Antigonid dynasty that succeeded Alexander the Great: Antigonus I Monophthalmus (382–301 BC) Antigonus II Gonatas (319–239 BC) Antigonus III Doson (263–221 BC) Antigonus, son of Echecrates, the nephew of Antigonus III Doson Antigonus II Mattathias (died 37 BC), last ruler of the Hasmonean kingdom of Judea

Military leaders Antigonus (Seleucid admiral), son of Menophilus, Seleucid admiral of the mid-2nd century BC Antigonus, a general of King Perseus in the Third Macedonian War, was sent to Aenia to guard the coast

Authors Antigonus (historian), Greek writer on history Antigonus of Alexandria, ancient Greek grammarian Antigonus of Carystus, 3rd century BC Greek writer on various subjects Antigonus of Cumae, ancient Greek writer on agriculture Antigonus of Sokho, Jewish scholar of the 3rd century BC Antigonus, writer on painting, mentioned by Diogenes Laërtius

Others Antigonus (physician), an ancient Greek surgeon Antigonus (sculptor), a Greek sculptor of the 3rd century BC Antigonos (son of Callas), Macedonian hetairos and athlete of the late 4th century BC Antigonus (butterfly), a genus of skipper butterflies Antigonus (character) from The Winter's Tale by William Shakespeare