Route 264 or Highway 264 may refer to:
Canada Manitoba Provincial Road 264 Prince Edward Island Route 264 Saskatchewan Highway 264
Israel Route 264 (Israel)
Japan Japan National Route 264
United Kingdom road B264 road
United States Interstate 264 (multiple highways) U.S. Route 264 Arizona State Route 264 Arkansas Highway 264 Georgia State Route 264 Indiana State Road 264 K-264 (Kansas highway) Maryland Route 264 Minnesota State Highway 264 Montana Secondary Highway 264 Nevada State Route 264 New Mexico State Road 264 New York State Route 264 Ohio State Route 264 Pennsylvania Route 264 (former) South Dakota Highway 264 (former) Tennessee State Route 264 Texas State Highway 264 (former) Texas State Highway Spur 264 Farm to Market Road 264 (Texas) Utah State Route 264 Virginia State Route 264