O'Hurley is a surname, and may refer to:
Dermot O'Hurley (c. 1530–1584), Irish Roman Catholic archbishop of Cashel. John O'Hurley (born 1954), American actor, voice actor, and television personality. Raymond O'Hurley (1909–1970), Canadian politician. As an Irish surname, it is associated with Clan Ó Comáin.
See also Hurley (disambiguation) Hurley (surname) O'Herlihy (surname)
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