The following highways are numbered 376:
Canada Nova Scotia Route 376 Saskatchewan Highway 376
Cuba
San Jose–La Ceiba Road (2–376)
Japan Japan National Route 376
United States Interstate 376 Interstate 376 Business Loop Florida State Road 376 (former) Georgia State Route 376 Iowa Highway 376 (unsigned designation for US 75 Bus.) Maryland Route 376 Missouri Route 376 Montana Secondary Highway 376 (former) Nevada State Route 376 New York State Route 376 Ohio State Route 376 Puerto Rico Highway 376 Virginia State Route 376 Wyoming Highway 376