Ophthalmotilapia is a small genus of four cichlid species endemic to Lake Tanganyika in East Africa.

Species There are currently four recognized species in this genus: Ophthalmotilapia boops (Boulenger, 1901) Ophthalmotilapia heterodonta (Poll & Matthes, 1962) Ophthalmotilapia nasuta (Poll & Matthes, 1962) Ophthalmotilapia ventralis (Boulenger, 1898)

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