EP1 or EP 1 may refer to:
Music EP 1 (Crosses EP), 2011 EP1 (dollys EP), 2013 EP1 (Duke Dumont EP), 2014 EP1 (FKA Twigs EP), 2012 EP1 (Kleptones EP), 2006 EP 1 (Odd Year and the Reverb Junkie EP), 2012 EP1 (Pixies EP), 2013 EP 1 (Qveen Herby EP), 2017 EP1 (Smoke & Jackal EP), 2012 EP 1 (Zero 7 EP), 2000 EP001, an EP by Thenewno2, 2006 EP 1, an EP by Basement Jaxx, 1994 EP1, an EP by Viktoria Modesta, 2010
Science Prostaglandin EP1 receptor, a human gene EP1 procyclin, a trypanosome procyclin protein
Transport EP1 (electric locomotive), a Russian locomotive New Haven EP-1, an electric locomotive built for the New York, New Haven and Hartford Railroad, 1905–1908
See also Episode I (disambiguation), the first release of any series EpOne, a 2000 EP by Hundred Reasons