Mathai () is a given name or surname, usually the Malayalam variant of Matthew, and may refer to:
Mathai (singer) (Sharon Mathai, born 1992), a contestant on season two of American TV series The Voice Mathai Joseph, Indian computer scientist Mathai Manjooran, Indian freedom fighter from Kerala A. M. Mathai (1935–2025), mathematician M. O. Mathai, Special assistant of the Prime Minister of India Jawaharlal Nehru Ranjan Mathai Varghese Mathai, mathematician and an Australian Research Council Senior Research Fellow at the University of Adelaide Wanjira Mathai (born 1971), Kenyan environmentalist
See also Matthew (name) Matthai