Luizão is a Portuguese nickname. It may refer to:
Luizão (footballer, born 1968), Brazilian football midfielder Luiz Antonio Ribeiro Luizão (footballer, born 1975), Brazilian football forward Luiz Carlos Bombonato Goulart Luizão (footballer, born 1980), Brazilian football defender Osvaldo Luiz Pereira Luizão (footballer, born 1987), Brazilian football defender Luiz Carlos Nascimento Júnior Luizão (footballer, born 1988), Brazilian football striker Luiz Fernando dos Santos Luizão (footballer, born 1990), Brazilian football centre-back Walter Luiz de Araújo Luizão (footballer, born 1998), Brazilian football midfielder Luiz Gustavo Novaes Palhares Luizão (footballer, born 2002), Brazilian football defender Luiz Gustavo Oliveira da Silva Luizão (footballer, born 2003), Brazilian football forward Luiz Guilherme Vieira da Silva Luizão Correa (born 1973), Brazilian beach volleyball player Luizão Maia (born 1949), Brazilian musician
See also Luisão (born 1981), Brazilian football defender Ânderson Luís da Silva