Prudhomme or Prud'homme may refer to:
Prudhomme (surname), a surname of French origin. The surname derives from the Old French prud'homme, meaning a wise, honest or sensible man. Prud'homme, Saskatchewan, a Canadian village Prudhomme Lake Provincial Park, in British Columbia, Canada Fort Prudhomme, a French fortification in Tennessee Narcisse Prudhomme Plantation in Bermuda, Louisiana
See also Perdomo (disambiguation), Spanish variant Prod'homme, a French automobile manufactured 1907 to 1908