Montelupo may refer to:

Places Domagnano, San Marino, formerly known as Montelupo after its coat of arms Montelupo Albese, Piedmont, Italy Montelupo Fiorentino, Tuscany, Italy Montelupo Observatory, an astronomic observatory in Montelupo Fiorentino

People Baccio da Montelupo (1469 – ), Italian sculptor Raffaello da Montelupo ( – c. 1566), Italian sculptor and architect, son of Baccio

Other uses 7198 Montelupo, a minor planet GP Montelupo, former cycling race in Montelupo Fiorentino