The Sisters of the Holy Family is the name for several different religious institutes of women in the Catholic Church:
The Sisters of the Holy Family (France), founded in Paris in 1806 by Jeanne-Claude Jacoulet in a revival of the Canonesses of St. Genevieve The Sisters of the Holy Family of Villefranche, founded by Émilie de Rodat in 1816 in Villefranche-de-Rouergue, France The Congregation of the Holy Family of Bordeaux, religious Sisters who are a part of the Association of the Holy Family of Bordeaux founded in 1820 by , a canon of that city The Sisters of the Holy Family (Louisiana), founded in 1837 by Henriette DeLille for African-American women The Sisters of the Holy Family of Helmet, founded in 1856 by three sisters, Rosalie, Henriette and Mélanie Van Biervliet, in Tielt, Belgium The Sisters of the Holy Family (California), founded in 1872 by Father John J. Prendergast and Lizzie Armer in San Francisco, California, United States The Sisters of the Holy Family of Nazareth, founded in 1875 in Rome, Italy, by Mother Mary of Jesus the Good Shepherd, a Polish noblewoman born Frances Siedliska