Lidoflazine is a piperazine calcium channel blocker. It is a coronary vasodilator with some antiarrhythmic action. Lidoflazine was discovered at Janssen Pharmaceutica in 1964. In 2025, Lidoflazine has also been reported to interact with tubulin and inhibit its polymerization.
Physical properties Solubility at room temperature
Extracted from Solvent 0.01 N 0.1 N % pH % pH Hydrochloric Acid 0.4 3.0 0.7 1.9 Tartaric Acid 0.3 3.1 1.0 2.5 Citric Acid 0.3 3.1 0.5 2.5 Lactic Acid 0.2 3.4 0.7 2.9 Acetic Acid 0.1 3.5 0.4 3.8
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