George Clerk may refer to:
Sir George Clerk, 6th Baronet (1787–1867), British politician Sir George Russell Clerk (1800–1889), civil servant in British India George Clerk (diplomat) (1874–1951), British diplomat George C. Clerk (1931–2019), Ghanaian botanist and plant pathologist
See also George Clerk-Maxwell (1715–1784), Scottish landowner George Clarke (disambiguation) George Clark (disambiguation) Clerk (disambiguation)