Saira may refer to:
People Nikolas Saira (born 1999), Finnish footballer Saira Banu (born 1944), Indian film actress Saira Elizabeth Luiza Shah (1900–1960), Scottish writer Saira Shah (born 1964), author, reporter and documentary filmmaker Saira Khan (born 1970), runner-up on the first series of The Apprentice (Great Britain) Saira Mohan (born 1978), Canadian fashion model of Indian, French and Irish descent Saira Choudhry (born 1988), British actress Saira Blair (born 1996), American politician Saira Khan (actress), Pakistani actress Saira Peter, fFirst Pakistani opera singer Saira Posada (born 1998), Spanish footballer Saira Wasim (born 1975), Pakistani artist
Other Cololabis saira, the scientific name of the Pacific saury fish Saira Batra, a character on the television series General Hospital: Night Shift Saira (character), the protagonist of the animated film Lesbian Space Princess (2025) Saira (film), a 2005 Malayalam-language Indian film starring Navya Nair and Nedumudi Venu Saira (video game), a computer game developed by Nifflas in 2009