Castel di Lama is a comune (municipality) in the Province of Ascoli Piceno in the Italian region Marche, located about south of Ancona and about east of Ascoli Piceno.
Castel di Lama borders the following 4 municipalities: Appignano del Tronto, Ascoli Piceno, Castorano, Offida.
The name comes from a medieval castle on the hill, which now houses the hotel Borgo Storico Seghetti Panichi.
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