Supple is a surname. Notable people with the surname include:
Barry Supple (born 1930), English academic Danton Supple (born 1965), British record producer John Supple (c. 1810–1869), Canadian businessman Shane Supple (born 1987), Irish footballer Tim Supple (born 1962), English theatre director
See also Violet Cliff (née Supple) (1916–2003), British skater Flexibility (disambiguation)