Brydon may refer to:
Brydon, West Virginia
People with the name Brydon Lynne Brydon (PhD 1976), British anthropologist and gender studies academic Mary Brydon, British nurse Paul Brydon (cyclist) (born 1951), New Zealand road and track cyclist Rob Brydon (born 1965), Welsh actor and comedian William Brydon (1811–1873), assistant surgeon in the British East India Company Army
See also Bryden, a surname Brydone, a surname