Leatherwood may refer to:
Plants Cyrilla, a plant genus of tropical to warm temperate Americas Dirca, a plant genus of temperate North America Eucryphia lucida, a plant species of Tasmania Macrolearia colensoi, a plant endemic to New Zealand
Places Leatherwood Plantation, a Virginia plantation once owned by Patrick Henry Leatherwood, Kentucky, an area in Perry County, Kentucky Leatherwood, Tennessee
Other uses Leatherwood (surname)
See also Leatherwood Creek (disambiguation)