Kaine is a surname. Notable people with the surname include:
Bill Kaine (1900–1968), English professional footballer Carmel Kaine (1937–2013), Australian classical violinist Jaiden Kaine, Cuban-American actor John Charles Kaine (1854–1923), Quebec politician Laurie Kaine (born 1952), Australian rules footballer Les Kaine (1936–2012), Australian rules footballer Obregon Kaine, main character in the comic book series Negation Tim Kaine (born 1958), American politician and 2016 Democratic Party vice presidential nominee Trevor Kaine (1928–2008), Australian politician Whitney Kaine (born 1956), American model
See also Kaine (disambiguation) Kane (disambiguation) Caine (disambiguation)