MLB usually refers to Major League Baseball, the highest level of professional baseball in North America.
MLB may also refer to:
Sports Minor League Baseball, more commonly abbreviated MiLB, a hierarchy of professional baseball leagues affiliated with Major League Baseball Middle linebacker, a position in American and Canadian football
Video games MLB (video game series), by 989 Sports Mario & Luigi: Brothership, an RPG game
Transportation Motor life boat Volkswagen Group MLB platform, for modular vehicle manufacture Melbourne Orlando International Airport, Florida, US, IATA code Maritime Labor Board, a US government agency that existed from 1938 to 1942
Other uses Morgan, Lewis & Bockius, an American multinational law firm Master of Law and Business, a degree awarded by Bucerius Law School Miłosz Biedrzycki, Polish poet
See also MLB.com, a domain name owned by Morgan, Lewis & Bockius, then transferred to Major League Baseball