2B is a character and one of the protagonists of the 2017 video game Nier: Automata.

2B or 2-B may also refer to:

Science IARC group 2B Type IIB string theory, a physical theory about the basic substance of the universe II-b or IIb, a subtype of Type II supernova Transcription factor II B, a type of protein structure Type IIb diamond, a classification of natural diamonds Alpha-2B adrenergic receptor, a type of protein structure

Sports and entertainment 2B (band), a Portuguese band 2B (film), a 2009 science fiction film 2b Theatre Company, a theatre company in Halifax, Nova Scotia 2b2t, а Minecraft server with no rules Second baseman, a fielding position in baseball Double (baseball), a type of base hit

Other uses 2B lead, a grading of pencil hardness Aerocondor, IATA airline code 2B Haute-Corse, French department 2B (northern Corsica) Stalag II-B, a prisoner of war camp in Germany

See also B2 (disambiguation) IIB (disambiguation) To Be (disambiguation)