Castell'Alfero () is a comune (municipality) in the Province of Asti in the Italian region Piedmont, located about east of Turin and about north of Asti.

Castell'Alfero borders the following municipalities: Asti, Calliano, Corsione, Cossombrato, Frinco, Tonco, and Villa San Secondo.

Twin towns Castell'Alfero is twinned with:

Lafrançaise, France

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