Lagerlöf is a Swedish surname. Notable people with the surname include:
Daniel Lind Lagerlöf (1969 – presumed 2011), Swedish film director Leon Lagerlöf (1870–1951), Swedish sport shooter Selma Lagerlöf (1858–1940), Swedish writer Thomas Lagerlöf (born 1971), Swedish association football coach
See also 11061 Lagerlöf, a main-belt asteroid