San Saba can refer to:
Places
Italy San Saba, Rome, a church in Rome, Italy San Saba, Lazio, a rione in the City of Rome
United States San Saba, Texas, a town in Texas, USA San Saba County, Texas, a county in Texas, USA San Saba River, a river in Texas Mission Santa Cruz de San Sabá, one of the Spanish missions in Texas
Other San Saba (film), a 2008 film starring Angus Macfadyen and Elisabeth Röhm