Rotolo is an Italian surname. Notable people with the surname include:

Antonio Rotolo (b. 1946), Sicilian mafiosi, an important member of Cosa Nostra Carla Rotolo (1941–2014), friend of Bob Dylan and sister of Suze Rotolo Mary Pezzati Rotolo (1910–1990), author and activist, mother of Suze and Carla Rotolo Stefania Rotolo (1951–1981), Italian singer and TV presenter Suze Rotolo (1943–2011), one of Bob Dylan's early girlfriends Tamara Rotolo, Californian mother of Jazmin Grace Grimaldi by Albert II, Prince of Monaco

Other Palazzo Rotolo, a 19th century historical building in Lercara Friddi, Sicily Rotolo (Italian for "roll"), an Italian pasta dish in which a filling is rolled up like a roulade in pasta sheets, poached, sliced, and then served.