Souther may refer to:
Souther (meteorology), a strong wind coming from the south
People Calvin Souther Fuller (1902–1994), American physical chemist and co-inventor of the solar cell Jack Souther (1924–2014), American-Canadian geologist JD Souther (1945–2024), American singer and songwriter John Souther (1816–1911), founder of Globe Locomotive Works Marguerite Souther (1882-1975) , dance educator, granddaughter of John Souther Michael Souther, Canadian television director, producer and writer Richard Souther (born 1951), American composer and instrumentalist
Places Souther Fell, a mountainous landscape in the English Lake District Souther Field, an airport in Americus, Georgia Airport
Other uses John Souther House, an historic house in Newton, Massachusetts, United States Souther, an antagonist in the manga/anime series Fist of the North Star
See also Southers, a military group in the comic strip Rogue Trooper Erroll Southers, 2009 nominee to be chief Administrator of the United States Transportation Security Administration