To Mega Therion (, ) may refer to:

The Beast (Revelation), one of three beasts described in the Book of Revelation Aleister Crowley (1875–1947), also known as To Mega Therion, English occultist Therion (band), formerly named Megatherion, a Swedish symphonic metal band "To Mega Therion", a song by Therion from the 1996 album Theli To Mega Therion (album), a 1985 album by Celtic Frost Tomegatherion, a fictional character in the video game Body Harvest

See also Megatherium, an extinct genus of ground sloths Therion (disambiguation)