Guanaco is an animal similar to the llama.

Guanaco may also refer to: An informal term for residents of El Salvador Guanaco hip hop, a style of music from El Salvador Guanaca language, also spelled Guanaco Guañacos, a village and municipality in Neuquén Province in southwestern Argentina

See also Río Guanaco, a hamlet on Navarino Island in the Tierra del Fuego archipelago in southern Chile