Hartshorne is a surname. Notable people with the surname include:
Anna Cope Hartshorne (1860–1957), American educator in Japan Arthur Hartshorne (1880–1915), American ice dancer Charles Hartshorne (1897–2000), American philosopher Charles Henry Hartshorne (1802–1865), English cleric and antiquary Edward Y. Hartshorne (1912–1946), American education officer Joshua Hartshorne (1808–1884), American politician from Pennsylvania Lawrence Hartshorne (1755–1822), merchant and political figure in Nova Scotia Lawrence Hartshorne, Jr. (1786–1865), hardware merchant and political figure in Nova Scotia Richard Hartshorne (1899–1992), American geographer Richard Hartshorne (settler) (1641–1722), early settler in New Jersey Richard Hartshorne (judge) (1888–1975), United States federal judge Robin Hartshorne (born 1938), American mathematician Sarah Hartshorne, contestant of America's Next Top Model, Cycle 9