The 1782 Mendoza earthquake took place in the province of Mendoza, Argentina, on 22 May 1782, at about 4p.m. (UTC-3). It had an estimated magnitude of 7.0 on the Richter scale. Its epicenter was at , at a depth of 30 km.

This was the first documented earthquake of the many that would affect the provincial capital of Mendoza since its foundation. It was felt with grade VIII (Severe) on the Mercalli intensity scale, and damaged several buildings, but did not produce casualties.

See also 1920 Mendoza earthquake

References Instituto Nacional de Prevención Sísmica. Listado de Terremotos Históricos.