Samoylov, Samoilov () or Samoilovs (Latvian transliteration) is a Russian masculine surname, its feminine counterpart is Samoylova Samoilova. It may refer to
Alexander Samoylov (1744–1814), a Russian general and statesman Alexander Filippovich Samoylov (1867-1930), Russian pioneer of electrocardiography Aleksandrs Samoilovs (born 1985), Latvian beach volleyball player Anton Samoylov (born 1983), Russian football player David Samoylov (1920–1990), Soviet poet Dmitri Samoylov (footballer, born 1990), Russian football player Dmitri Samoylov (footballer, born 1993), Russian football player Dmitry Samoylov (pilot) (1922-2012), Soviet fighter pilot Inna Sergeyevna Shcherbina-Samoylova (1922-2003), Russian astronomer and astrophysicist Konkordiya Samoilova (1876–1921), Russian bolshevik Maksim Samoylov (1981–2024), Russian football player Oksana Samoylova (born 1988), Russian model Pavel Samoylov (born 1982), Russian football player Tatiana Samoylova (1934–2014), Russian and Soviet actress Vadim and Gleb Samoylov, leaders of the Russian rock band Agatha Christie (band) Vasily Samoylov (1813–1887), Russian actor Vitali Samoilov (born 1962), Russian-born Latvian ice-hockey player Vitaliy Samoylov (born 1975), Ukrainian football player Yekaterina Samoylova (1763–1830), Russian noble and lady-in-waiting Yevgeny Samoylov (1912–2006), a Soviet actor Yuliya Samoylova (born 1989), Russian singer Countess Yuliya Samoylova (1803–1875)