Grigsby is an English surname derived from the name of a "lost" medieval village in Lincolnshire recorded in the Domesday Book as "Gredbi", which was itself a development of the Old Norse "Griot-byr".SurnameDB, https://www.surnamedb.com/Surname/Grigsby#ixzz6qPckMynS The spelling "Grigsby" is believed to stem from a common progenitor, John Grigsby (1623–1730). Most Grigsbys in the United States trace their descent from this 17th-century landowner, in Stafford County, Virginia.

People named Grigsby Andrew Jackson Grigsby (1819–1895), colonel for the Stonewall Brigade for the Confederate States Army in the American Civil War, and commander in the Battle of Antietam Beverly Grigsby (1928–2022), American musician Bill Grigsby (1922–2011), announcer for the Kansas City Chiefs Boomer Grigsby (born 1981), American football fullback Charles Grigsby (born 1978), American Idol contestant Chuck Grigsby (1928–2003), American basketball player Denver Grigsby (1901–1973), Major League Baseball outfielder Elisenda Grigsby, American mathematician Gary Grigsby, American game designer George Barnes Grigsby (1874–1962), delegate to the United States House of Representatives from the Territory of Alaska Hugh Blair Grigsby (1806–1881), Virginia statesman and historian J. Eugene Grigsby (1918–2013), American multimedia artist Jill S. Grigsby (born 1954), American sociologist John Grigsby, captain in the United States Army, leader in the Bear Flag Revolt and the Grigsby-Ide Party Lewis Grigsby (1867–1932), American real estate investor Margaret E. Grigsby (1923–2009), African American woman physician Melvin Grigsby (1845–1917), Attorney General of South Dakota Michael Grigsby (1936–2013), British filmmaker Nic Grigsby (born 1988), Canadian football running back Nicholas Grigsby (American football) (born 1992), American football linebacker Noel Grigsby (born 1991), American football wide receiver Otis Grigsby (born 1980), American football defensive end Pearl Grigsby Richardson (1896–1983), American educator, clubwoman Sioux K. Grigsby (1873–1968), Lieutenant Governor of South Dakota Tamara Grigsby (1974–2016), representative for the Wisconsin State Assembly Wayne Grigsby (born 1947), Canadian screenwriter and producer Will Grigsby (born 1970), American IBF light flyweight champion boxer

See also Grigsby, Kentucky

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